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Home  >  Problems  >  Chapter 13

Problems 2-4 require that BioConductor be set up by the Instructor or computer support person. The 95-gene set used for many examples in the chapter may be downloaded from the book Web site and sample scripts are shown in the chapter (Tables 13.5 and 13.8).

2. Use the marray package in BioConductor to create an M/A plot with the maPlot function for the small 95-gene data set. Do so first without background adjustment and then with background adjustment. What impact does background adjustment have on the variation? Is the impact constant with the level of expression?


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