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6. In addition to individual genes, whole genomes of organisms are becoming available, including many prokaryotes, organelles, and viruses. One good way to retrieve these genomic sequences is through the NCBI Entrez page for genomes and the taxonomy browser.
  1. Go to the NCBI Entrez page and then to the genome page (on bar at top of Entrez page). Enter "Homo sapiens mitochondrion" and click on the entry that appears for the human mitochondrion. Note that the RefSeq accession number starts with NC (nucleotide sequence of chromosome). Examine the sequence of the Homo sapiens mitochondria. What is the length? Roughly outline the genes that are present. Click on the map to see the genes that are present and then on the gene blocks to see the sequences.
  2. Another resource for microbial genomes is at the The Institute for Genomic Research. Go to the Comprehensive Microbial Resource page, choose genomes, and click on the genome name of Synechocystis sp. PCC 6803 under the group Cyanobacteria. This is an ancient organism that produces oxygen from light and puts oxygen in the atmosphere. What is the size of the genome and how many proteins are encoded? What does the color code of the genome represent?


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